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Fig. 14.
Schematic of Britten-Davidson generalized "operon-operator" model for gene regulation in higher cells |
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Translated to the broadcast language a sensor-integrator gene complex SI1I2I3 is directly represented by the set of broadcast units *S:I1*S:I2*S:I3. A receptor-producer complex R1R2P is similarly represented by *R1:P*R2:P. If the receptor R1 responds only to the integrator I3, say, then *R1:P would be replaced by *I3:P. It is apparent, however, that the receptor R1 could be activated by several related signals, say IA, IB, IC, . . ., in which case the producer complex would be represented by . Similarly a sensor S could be sensitive to any product with an initial radical X so that SI1I2I3 could be represented by . Clearly extremely complex feedback loops can be constructed, allowing a great range of conditional actions dependent upon substrate and products already pro- |
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